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Tirzepatide is the agonist of GLP-1 receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor, which can reduce body weight and improve cardiac metabolism by subcutaneous injection once a week (Jastreboff et al 2022)

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Our findings suggest that significant postoperative weight loss is associated with an increased risk of developing stoma-related complications, highlighting the importance of nutritional monitoring and early intervention after surgery

Consulting with your weight loss clinic or doctor is the first step

Bleeding risk assessment should be performed before initiating either medication class

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