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doi: 10.1155/2019/4050796

GLP-1 RA, glucagon-like peptide-1 receptor agonist

TGR5-deficient mice have increased colonic mucosal permeability, through disruption of epithelial tight junctions (176)

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You dont want to get a prescription and walk awaythats not going to work in the long term. About half of patients who start a GLP-1 medication stop within a year, he notes, often because of side effects, cost, or lack of follow-up