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Discontinuation rates in ATTAIN trials were higher with Foundayo than placebo, mostly due to persistent GI effects
While Semaglutide supports caloric control and weight management , Tirzepatides dual pathway may provide an advantage in fat oxidation and metabolic efficiency
Clinicians should also be mindful of the risk for constipation with GLP-1 RAs and counsel patients on preventive measures for constipation, as well as prescribe laxative agents when appropriate
Effects of folic acid on oligozoospermia with MTHFR polymorphisms in term of seminal parameters, DNA fragmentation, and live birth rate: a double-blind, randomized, placebo-controlled trial