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However, if heart rate effects are accompanied by palpitations, chest discomfort, or significant exercise intolerance, dose reduction is appropriate

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GLP-1RAs and SGLT2 inhibitors also have pleiotropic effects, including blood glucose-dependent and -independent mechanisms, effects on the reninangiotensinaldosterone system and favourable effects on left ventricular and renal functions [35, 36]

For patients balancing cardiovascular risk, the article Wegovy and Your Heart explains how fluids and pressure control intersect with kidney safety

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The potential of mesenchymal stem cells in the management of radiation enteropathy