Combination therapy was associated with a lower risk of primary composite outcomes of all-cause hospitalization, all-cause mortality, major adverse cardiovascular events (MACE), major adverse kidney events (MAKE), and major adverse liver outcomes (MALO) (hazard ratio [HR], 0.87
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Longer follow-up times of six months or 12 months revealed decreases in testosterone and fasting insulin, blood glucose, and triglyceride levels
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Applying the same distance constraints as for ProteinMPNN, we designed and experimentally assayed 82 PROSS-generated variants for activity and soluble yield
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