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Gallbladder problems , including gallstones, have also been associated with GLP-1 therapy, likely related to rapid weight loss and changes in bile composition

Severe gastrointestinal conditions Conditions like gastroparesis (delayed stomach emptying) may be worsened by GLP-1 medications, which slow gastric motility further

These changes generally occur because GLP-1 receptor activation fundamentally alters the coordinated muscular contractions (peristalsis) that move contents through your intestines

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We compared the SNP effect among people treated with semaglutide versus tirzepatide (Extended Data Fig

Within six to eight weeks of use, you will start getting results