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Epithalon is a short synthetic tetrapeptide (Ala-Glu-Asp-Gly) with a chemical structure that is being investigated as a potential activator of the telomerase enzyme and stimulant of melatonin release

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Analysis of these proteins by DSC revealed that the folded structures are located entirely within these peptides, whereas a thermorgram of the C-terminal domain of H1 contains no peak and shows high C p values, thereby indicating that this domain is not folded (Crane-Robinson and Privalov, 1983)

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