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Unlike the damage induced by glutamate, excessive activation of GABA A receptors induced widespread cell death in the hippocampus in both males and females, although the damage was slightly but significantly greater in males (150, 151)

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The mechanism of action of semaglutide involves mimicking the effects of the naturally occurring hormone GLP-1

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The best outcomes with GLP-1 medications come from people who use reduced appetite as an opportunity to build sustainable eating habits, not as a replacement for any attention to nutrition or activity