As compared to placebo, all doses of tirzepatide and semaglutide increased risk for gastrointestinal adverse events, with tirzepatide 15mg yielding the highest increased risk (3.6 times) for nausea, vomiting (4.4 times) and diarrhoea (double the risk)
The small amount wasted is worth the dosing accuracy gained
This injectable medication works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways
Oral semaglutide exists (brand name Rybelsus), but it requires a specific formulation with SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate) to survive stomach acid
Ozempic Can Cause Major Loss of Muscle Mass and Reduce Bone Density
By staying informed and proactive about your health, you can mitigate risks and ensure optimal well-being