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Serotypes such as AAV1, AAV6, AAV8, and especially AAV9 have demonstrated efficient cardiac transduction in small and large animals, enabling robust gene transfer to myocardium with intracoronary or intravenous delivery (Mazurek et al., 2024)

Immunogenicity of Biotherapeutics: Causes and Association with Posttranslational Modifications

Gupta, S

For people with problems absorbing the vitamin, pregnant women, and individuals suffering from mild deficiency, a 1000 mcg dose may be recommended

LLPS occurs in glial cell types, including astrocytes, microglia, and oligodendrocytes, where its dysregulation is implicated in neuroinflammation, demyelination, and the pathogenesis of neurodegenerative diseases

Sahoo DK, Samanta L, Kesari KK, Mukherjee S