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Despite the use of 20 mg tamoxifen twice daily, there was no significant improvement in pain, curvature, or plaque size when compared to placebo (19)
While most reactions are mild and self-limiting, patients should monitor their response and contact their healthcare provider if they experience severe or persistent symptoms that dont improve over time
Interestingly, vitamin D supplementation alone lowered estradiol but improved vitamin D status
Those who lost weight rapidly tend to regain more quickly than those with slower, steadier progress