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Lean mass, especially skeletal muscle, is central to strength, stamina and blood sugar regulation, and so its loss is potentially harmful, explains Dr Panella

Once tirzepatide has been thawed from freezing, it should never be placed back in the freezer

doi: 10.7554/eLife.01293 18 ZhangMMWuP-YJKellyFDNursePHangHC

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Younk LM, Mikeladze M, Tate D, Davis SN