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The vegetarian capsule and straightforward excipient list make it accessible for most healthy adults

Shortly after being sued by the Outsourcing Facilities Assn., a compounding trade group, the FDA reversed its decision and said it would allow pharmacists to continue making compounded versions of the drug while it reexamines the shortage

Long-term cardiovascular outcome data from the SURPASS-CVOT trial are expected in 2025 to further establish safety and efficacy

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That means the worsening on re-escalation is tangled up with drug accumulation and cannot be put down to the dose increase alone, which softens the rechallenge-dependent Naranjo items and the dose-dependence story along with them