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GLP-1 medications cause constipation by slowing gastric emptying and overall gut transit time Macrogol preparations retain water in stool and are recommended for long-term use with GLP-1 therapy Bulk-forming laxatives like ispaghula husk are first-line treatment according to NICE guidance Adequate hydration (1.52 litres daily) is essential when using laxatives with GLP-1 medications Patients should seek medical advice if constipation persists beyond 12 weeks despite treatment Table of Contents Have questions about Wegovy

However, it does not appear to have the same effect on obese test subjects as we read in the following PubMed study quote: In obese subjects, acute administration of the weight-loss supplement CM3 (a type of cellulose fiber) does not delay gastric emptying and does not influence subjective appetite sensations

[89] Sources: PMC12752444 (meta-analysis on GLP-1 effects on testosterone)

These medications: Increase satiety Reduce appetite Slow digestion However, these treatments require injections, medical supervision, and ongoing use

So you lose a lot of the volume out of the butt

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