39% (suboptimal) and 46% (clinically active) weight loss in the DIO mouse model
Mice were on C57BL/6 background (The Jackson Laboratory), fed either chow diet (Mouse Diet 9F, PharmaServ) or HFD (Research Diets, D12492)
A study measuring only serum KLOW concentration would conclude the compound is "gone" by 48 hours, but tissue samples taken at 7296 hours post-administration still show elevated phosphorylated AMPK levels, indicating ongoing metabolic effects
Cng mt s thnh phn khc : Sodium Hyaluronate, Sunflower Seed Oil, Zanthoxylum Piperitum Fruit Extract, Usnea Barbata Extract, Pulsatilla Koreana Extract, Cetearyl Olivate, Sorbitan Olivate, Glycerin, Niacin, Retinyl Palmitate, Biotin, Butylene Glycol, Ascorbyl Glucoside, Water, Carnitine Hcl, Caprylyl Glycol, Caprylhydroxamic Acid, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-16, SH-Polypeptide-3, Sh-Polypeptide-4, Ethanol, Octoxynol-9, Olea Europaea Leaf Extract, Polysorbate 20
[DOI] [PubMed] [Google Scholar] 43
(PubMed) Lampeter EF, Klinghammer A, Scherbaum WA, et al