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Scarce but promising evidence for role of alogliptin on cardiovascular system and bone metabolism are reported

Controlled oral studies have produced mixed results

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Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems

The changes in the gut microbiota have the potential to influence immune system pathways and become key contributors to SLE pathology

(Figure 1) Figure 1: Mean insulin concentration at 0-120 minutes during hyperglycemic clamp at baseline and Week 28 Insulin Sensitivity Tirzepatide increases insulin sensitivity, as demonstrated in a hyperinsulinemic euglycemic clamp study after 28 weeks of treatment