207.3 PROtocols matter: A systematised evaluation of adherence to Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) patient-reported outcome guidelines in interventional paediatric oncology trials Denise Connolly 1 , Sarah Cohen-Gogo 1 , Sharon De Graves 2 1 The Hospital for Sick Children, Toronto, Ontario, Canada, 2 University of Melbourne, Melbourne, Australia Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :207.3 Aims Despite increasing recognition of their importance, patient-reported outcomes (PROs) remain poorly implemented in interventional paediatric oncology trials
Firstly, incomplete data for several outcomes, due to the retrospective design, may have affected our estimations
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This long-term storage capability in the liver ensures that the body has a reserve of vitamin B12 that can be utilized over extended periods
These results demonstrate that the observed analgesic effects of 2MT are not attributable to motor impairment
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