effectively uh basically buying them sort of off the shelf and illegally per se through online sources well what's the issue with that well according to a twenty twenty four study the actual purity of some of these compounds is anywhere from 7.7 to 14.3 percent in this sample from this this study uh that's definitely concerning because you can see that if you're not getting the right dose you could have adverse effects or you may try to take more right well the other other issues patients have tried other medications like say or excuse me supplements like berberine we talked about this in our second video berberine helps with the insulin response it can help a lower blood sugar some people say it's sort of like the natural glp but it really isn't it acts on a different completely different pathway and so what patients sometimes will do is double up they'll they'll have berberine or this gray market glp or the gray market glp is just berberine right and so they don't really know what they're getting and that's the issue with not having that regulation and and inspection so what does this mean well poison control calls over the last several years are up over one thousand percent uh related to complications from GLP, particularly injections and mixing

When to escalate If you have consistently implemented this entire protocol for 3-4 weeks and still experience fewer than 3 bowel movements per week with significant discomfort, it is time to involve your healthcare provider
These medications are relatively expensive and patients may need to use them continuously to maintain weight loss
Likewise, you might be able to get your GLP-1 RA approved based on one of your conditions rather than another
In addition, the change of bile acid concentration during weight loss metabolic surgery is also controversial
As cells composed of high levels of mitochondria, RGCs maintain a balanced microenvironment via the tight regulation of mitochondria integrity through the process of mitophagya PINK/Parkin-dependent pathway