However, a growing body of evidence now unequivocally demonstrates that smoking negatively influences the incidence, severity, and outcomes of a wide spectrum of hepatic conditions, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), chronic viral hepatitis (HBV and HCV), primary biliary cholangitis (PBC), and hepatocellular carcinoma (HCC)
(2019, February 27)
Intriguingly, a recently published article explored the involvement of the gut-retina axis in retinal ferroptosis
Key advancements in peptide technology for triple receptor agonism: Application of computational modeling to peptide-receptor binding Fatty acid substitution for extended stability and duration -helical design for superior receptor fit Structure-based design to hone drug action and safety Engineering peptides that simultaneously bind and stimulate multiple receptors Clinical Implications With retatrutide, a triple receptor agonist that has been studied in clinical trials for obesity and metabolic diseases, including type 2 diabetes and MASLD
10.1186/s43094-022-00402-y 105 KuoH.-C.HuangC.-C.ChuC.-C.KaoL.-Y.LeeH.-C.PangC.-Y.et al
Plus, cutting out foods and drinks high in added sugars can reduce the risk of heart disease and type 2 diabetes (14,15)