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In one small study, most patients who switched from metformin IR to XR reported improvement in GI AEs (e.g., diarrhea) [77]

This is particularly beneficial for skin health, as the body undergoes significant repair during sleep

Statements Author contributions MM-T wrote the first draft of the manuscript

Drafting the work or revising: H.S.B., S.H.L., J.H.C., T.S.S., H.S.S., K.H.Y., E.Y.L

There are two primary ways healthcare professionals handle this transition: the Washout method and the Direct Switch method

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