Signs of more severe dehydration include (9): Little to no urination, or very dark yellow or amber-colored urine Dry, shriveled-looking skin Dizziness or lightheadedness Irritability or confusion Rapid heartbeat Rapid breathing Sunken eyes Extreme tiredness or listlessness In severe cases, shock or loss of consciousness Spotting these signs early can help you take action before dehydration becomes a bigger issue, especially if youre managing side effects from GLP-1 medications
Oral formulations have a shorter half-life.[ref] In clinical trials, GLP-1 RAs improved lipid profiles, increased satiety, slowed gastric emptying, reduced inflammation, and had neuroprotective effects.[ref] The slowing of gastric emptying and reducing inflammation may play a role in weight loss, along with the decrease in appetite and eating less
UK regulatory data from the MHRA and EMA have not highlighted cognitive impairment as a safety concern for this medication class
Effects of intense exercise and moderate caloric restriction on cardiovascular risk factors and inflammation
Analysis of relative gene expression data using real-time quantitative PCR and the 2-CT method
Development of a gut microbetargeted nonlethal therapeutic to inhibit thrombosis potential