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Los AR GLP-1 de accin corta determinan una reduccin importante de la GPP, si bien el mecanismo no es mediado por la estimulacin de la secrecin de insulina post ingesta, que curiosamente se encuentra disminuida tras las administracin de este grupo teraputico, sino que se ha descrito como principal mecanismo implicado el retraso del vaciamiento gstrico y el consiguiente aumento de la absorcin de la glucosa esplcnica

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Metrology data are presented as the mean plus or minus the standard error (s)

Each tub contains100 servingsat 1 g per scoop

Key results at 80 weeks: Participants on the 4 mg dose lost an average of 47.2 lbs (19.0%) Participants on the 12 mg dose lost an average of 70.3 lbs (28.3%) 45.3% of participants on the 12 mg dose achieved at least 30% weight loss a level historically associated with bariatric surgery outcomes The 4 mg dose showed a lower rate of discontinuation due to adverse events than even placebo In a study extension to 104 weeks, participants with a starting BMI of 35 or higher who received 12 mg lost up to an average of 85.0 lbs (30.3%)