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Furthermore, therapeutic mechanisms such as alternative splicing ASOs that have FDA approval for non-NDD pathologies such as Spinraza (SMA) and Eteplirsen (DMD) may provide a strong basis for further studies using these ASOs for genes with splice mutations implicated in NDDs

Histological analysis further supported these behavioral findings, showing partial restoration of tyrosine hydroxylase staining in the substantia nigra of Dihexa-treated animals, indicative of neuronal protection and recovery [2]

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El TB-500 (TB 500 peptide) es un fragmento sinttico de la timosina 4

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