The most common side effect described, with respect to the total number of related topics, groups, and discussions, was nausea, followed by vomiting, constipation, injection site issues, pancreatitis, and gastroparesis
The ABC contacted the TGA for comment
Additionally, muscle injection creates localized pain, bruising, and potential nerve irritation that subcutaneous injection typically avoids
[PubMed] [Google Scholar] 480
Semaglutide activates only the GLP-1 receptor, while tirzepatide activates both GLP-1 and GIP receptorsa dual-agonist approach that has shown numerically larger weight reductions in clinical trials
Another practical catch: EGF is a fragile protein so it reacts badly to heat and the wrong pH