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The Wall Street Journal

Astrocytic reactivity reflects activation of complex molecularly defined programmes which define remodelling of biochemical, morphological, metabolic, and physiological properties of astroglia leading to an upregulation or loss of homoeostatic cascades, or in gain of new protective or regenerative functions

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From Metformin improving insulin sensitivity to SGLT2 inhibitors promoting glucose excretion, each class has unique benefitsand risks