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Combining this with biochemical indicators, such as blood glucose levels, calcium-phosphorus metabolism, and bone turnover markers, can offer a more comprehensive understanding of the patients bone health

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During breast cancer, tumor cells recruit resident fibroblasts [57], adipocytes [58], and/or bone marrow-derived mesenchymal stem cells [59], transforming them into cancer-associated fibroblasts (CAFs), which in turn reshape and remodel the tumor microenvironment

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