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12 week cycles are optimal*

Table 1: Diagnosing gout when no crystal identification is possible Ideally, 6 of 10 features will be present of the following: Inflammation reaches a maximum within one day (rapid acceleration of inflammation)

Cycle Guidelines Approach Standard Duration 4-6 weeks Review point Week 4 Best for General research planning Approach Extended Duration 6-8 weeks Review point Week 6 Best for Stubborn-injury research models Approach Long Duration 8-12 weeks Review point Week 8 Best for Slow-remodeling tissue research planning Off periods of 2-4 weeks between cycles are common in research planning