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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

If its Zepbound, find the vial price your maintenance dose lands in ($299 to $699), and weigh it against the roughly $550 savings-card route if you hold commercial insurance that excludes the drug

800+ lives transformed 24/7 access to the patient portal for any questions or concerns

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Tirzepatide is technically a dual GIP and GLP-1 receptor agonist, but many patients group it with GLP-1 weight-loss injections because it affects the GLP-1 pathway

Euro J Pharmac Sci