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Clinicians should apply clinical judgement to select an individualised approach and may choose between: A one-to-two-week washout before semaglutide initiation, which is preferred for patients with significant side effects

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For type 2 diabetes , GLP-1 receptor agonists are generally considered a long-term treatment, as diabetes is a chronic progressive condition requiring ongoing management

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Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures