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There is every reason to argue that the efficacy observed for compounds 1 and 2 in vivo incorporates a similar role for the host immune response as seen for other schistosomicidal agents

In the context of a low-carb ancestral diet thats better aligned with our physiology, vitamin C deficiency is likely not an issue

Immunological tolerance: the key feature in human filariasis

Biochemically, ALA serves as an absolutely essential cofactor for several key mitochondrial enzyme complexes involved in energy metabolism

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