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Medication-specific factors require consideration of pharmacokinetic properties, with weekly formulations potentially having more prolonged effects than daily preparations [51]

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Microdose GLP-1 uses a much lower dose than standard treatments

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In parallel, excessive Cu + generated in GSH-rich reductive environments can bind lipoylated mitochondrial TCA-cycle proteins such as DLAT, inducing aberrant protein aggregation and triggering cuproptosis across multiple cancer types 187,189,192-194

PMCID: PMC11909624