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The buffering genetic interaction revealed from our CRISPR screen 13 allowed further extending the finding by demonstrating a functional coordination of mitochondrial glutathione uptake (mediated by SLC25A39) and mitochondrial iron import (mediated by SLC25A37) in supporting OXPHOS

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He said he no longer qualified for the drug because he'd successfully lost more weight and controlled food noise using it

Molina-Holgado et al., 2022)

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Moreover, the Oxidative stress evaluation showed that PMMSN substantially enhanced oxidative stress in tumor cells, as suggested by a marked rise in ROS production observed using fluorescence microscopy and quantified by higher MDA levels and lower SOD and GSH-Px levels compared to control and PMSN