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Research into semaglutide and vision loss has expanded rapidly as physicians investigate reports of non-arteritic anterior ischemic optic neuropathy (NAION), a condition involving reduced blood flow to the optic nerve that can cause sudden, painless vision loss

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Mediators stimulating C-fibers vary: in dogs, pulmonary subtypes do not (but bronchial subtypes do) respond to histamine, and in other animal models, they do not respond to serotonin or adenosine

Of course, this solution is not tenable when delivering the peptide orally and so scientists set out to produce a more stable form of BPC 157 by adding additional chemical structures to the peptide that resist gastric acid but do not alter overall function

Rathore SS, Radford MJ, Krumholz HM