Energy Production : Iron aids in the production of ATP (adenosine triphosphate), the energy currency of our cells, by assisting in metabolic processes
Activated ATF4 could transcribe System Xc-, promote GSH expression to elevate antioxidant capacity, and inhibit cellular ferroptosis, whereas knockdown of ATF4 caused ROS accumulation, inducing ferroptosis
It also helps with weight loss, heart health, and brain function
The resulting consequences-oxidative stress, permeability transition, mtDNA release, and apoptosis-profoundly impact disease pathogenesis
At the initial visit, subjects completed all pre-diet baseline measures, including measurement of anthropometrics and the excitotoxin food-frequency questionnaire (FFQ)
doi: 10.7717/peerj.2292