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During the day, symptoms often occur when holding something for a prolonged period of time with the wrist bent forward or backward, such as when using a phone, driving, or reading a book
Furthermore, the metabolism of 2-EH and 2-EHALD by the action of an NAD + -independent alcohol/aldehyde dehydrogenase (oxidoreductase) was supported by dye-linked assay for NAD(P) + -independent dehydrogenase activity [38, 39] towards 2-EH and 2-EHALD using 2,6-dichlorophenol indophenol (DCPIP) as the ultimate electron acceptor (Additional file 5: Figure S4)
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doi: 10.1038/modpathol.3800933