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Initial investigations into the cardiovascular safety effects of glucose-lowering medications in patients with T2D revealed an unexpected reduction in CV complications and mortality with the use glucagon-like peptide 1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is)
Being aware of these risks is important
GLP-1 agonists should also be avoided by those with a history of thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2), as these conditions may increase the risk of medullary thyroid carcinoma
P 60%), as the result was not statistically significant (RR 0.87
GLP-1 semaglutide medication mimics the GLP-1 hormone that is known to increase feelings of fullness and slows gastric emptying, further increasing the feeling of fullness
Wegovy Metabolic DysfunctionAssociated Steatohepatitis (MASH) Coverage may be possible for patients with: Moderate to advanced fibrosis (F2F3) Supporting documentation may be required
