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Antithrombotic Effects GLP-1 agonists reduce cardiovascular events through several mechanisms previously summarized to include improved glycemic control, weight loss, lowering blood pressure, lipid lowering, reduced atherogenesis, attenuated vascular inflammation, improved endothelial cell function, vasodilation, and direct cardiovascular protective effects [88, 89]

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Users lose weight during active treatment, attempt maintenance through lifestyle alone, then restart medication when regain reaches a predetermined threshold (often 10 to 15 pounds)

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