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Studies in humans have also confirmed that consuming fat and sugar simultaneously promotes overeating (Hedrih, 2024), likely due to increased reward responses from separate neural gut-brain pathways activated by sugar and fat (McDougle et al., 2024)

Thus, the greater efficacy of inhibitor 2 observed against adult worms, translated to the greater efficacy in mice against juvenile worms

15 Likewise, free radicals have dual actions depending on their concentration

Casiraghi, M

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When given to obese mice, LY3437943 decreased body weight and enhanced glycemic/blood sugar control