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doi:10.1016/j.mam.2008.05.005

In order to induce T lymphocyte apoptosis, GSH must be pumped out of the cells (Franco and Cidlowski, 2006, 2012

While unconjugated monoclonal antibodies generally have half-lives of 1 to 3 weeks, ADCs often exhibit significantly shorter half-lives of just only 2 to 5 days

Using gene expression data from the Broad Institute's measurement of 13,424 human genes, analysis revealed GHK increases gene expression in 59% of affected genes while suppressing expression in 41%