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A 24% figure at 48 weeks and a 22.5% figure at 72 weeks are not measuring the same thing

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27 , 28 Dosage Berberine is generally considered safe up to 200300 mg TID

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First, the molecular trigger specificity of oxalate-induced ferroptosis in renal tubular cells is undefinedhow oxalate precisely initiates the synergistic dysregulation of iron uptake (TFR1), lipid metabolism (ACSL4), and antioxidant defense (GPX4/SLC7A11) remains elusive, with no clarity on upstream signaling molecules or post-translational modifications that link oxalate exposure to ferroptosis machinery

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