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Notably, deletion of the equilibrative nucleoside transporter 1 (ENT1) leads to reduced AQP4 expression, further linking purinergic signaling to astrocytic water channel regulation [422]

The DNA sequence spanning the CBS gene ARE motif located 4970 bp upstream of the transcript start site and its mutants were cloned into a GFP expressing reporter pEGFP-N1 (PT3054, Clontech) with sequence specific primers (Supplementary Table 1)

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Prohibitin plays a role in the functional plasticity of macrophages