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For GLP-1 medications, follow the specific Instructions for Use (IFU) for your product, as handling varies significantly between devices: For Ozempic (semaglutide) multi-dose pens: Perform a flow check only before the first use of each new pen Attach a new needle, turn the dose selector to the flow check symbol (not your treatment dose) Hold the pen with the needle pointing upward and tap gently to move air bubbles to the top Press the dose button completely until you see a drop of medication at the needle tip Do not repeat this process before each dose

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