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The first divergently transcribed operon encodes for two proteins of unknown function, two candidate COG0523-family putative Zn metallochaperones, the DksA2 paralog, and a TonB transporter component that may be involved in Zn uptake across the outer membrane in this Gram-negative bacterium, through the outer membrane porin ZnuD

PMID 18177285

PMCID: PMC8622150

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Same drug, same receptor occupancy, different cascade output

The Alzheimer Drug Discovery Foundation rated cerebrolysin as potentially useful, noting that while results from several clinical trials suggest small improvements to symptoms of Alzheimer disease and vascular dementia , the effects are generally lower than those of currently approved drugs like donepezil or memantine