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J Pharm Exp Ther

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Herein, paracetamol-induced lipid peroxidation was detected in the rats, as demonstrated by the increased MDA levels and decreased GSH, SOD, and CAT levels in the liver tissues, all of which are key antioxidant indicators

It is widely accepted that alcohol use and a number of pharmacological agents, for example isoniazid, induce expression of CYP2E1 (see section Potential drug interactions with paracetamol metabolism and section Alcohol use)

Altogether, these insights underscore the importance of integrating mechanistic, molecular, and epidemiological data, not only to deepen our understanding of the strength and nature of the relationship between NSW and BC, but also to support a precision medicine framework