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High-dose oral supplements (often 10002000 micrograms daily) or intramuscular injections (typically 1mg hydroxocobalamin) used to treat pernicious anaemia or deficiency states can temporarily elevate serum levels

Vitamin B12 shots may be beneficial for those who are vitamin B12 deficient due to pernicious anemia, dietary deficiency (often from vegan or vegetarian diets), gastrointestinal surgery, and more

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PlexusDx patients should confirm their needle specifications with their injection kit instructions, as compounded semaglutide from licensed 503A compounding pharmacies may arrive with pre-filled pens or vials that specify compatible needle types

If weight was lost because of poor appetite related to deficiency, regaining weight may occur over weeks to months after replacement