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The drugs ability to decrease intake and preference for rewarding foods suggests a broader suppressive effect on motivation for rewards, which may be beneficial for individuals with addictive behaviors beyond alcohol. Drinking alcohol is common in many cultures and countries

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Reproducibility, scalability, and safety concerns may limit fecal FMT practice

NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% in diet-induced obese mouse models without suppressing food intake, suggesting energy expenditure modulation

95% CI, 8.44 to 1.21

In mouse primary chondrocytes stimulated with IL-1, liraglutide treatment downregulated Tnf and nitric oxide synthase 2 (Nos2)