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Evans RW, Shaten BJ, Hempel JD, Cutler JA, and Kuller LH (1997)
Although, in many cases, BBTB can severely limit drug transport, these alterations in BBTB enhance the penetration of chemotherapeutic agents compared to intact BBB[61]
Nevertheless, promising preclinical and observational findings have not been mirrored in clinical success for the treatment of established AD
In this context, a promising newcomer among rodents considers the spiny mouse, which has a longer gestational duration than the mouse with organogenesis completed at birth
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