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In the SURMOUNT-1 trial, people taking tirzepatide (Zepbound) lost an average of 22.5% of their body weight over 72 weeks

Use increases with age, peaking at 33.3% in the 5064 age group before declining to 20.8% among those 65 and older

Since retatrutide activates GIP receptors that enhance insulin sensitivity, some researchers theorize that morning injection could synergize with the natural morning insulin sensitivity peak to produce slightly better metabolic outcomes

It is especially advantageous to people suffering from CFS (chronic fatigue syndrome), since it reduces the severity of symptoms

With WeGovy we see roughly +/- 10% while with Mounjaro, its roughly +15%/-10%, compared to much larger swings with the 7-day dosing

However, buyers and prospective buyers should monitor FDA announcements and the brand's communications for any future regulatory changes