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They stimulate insulin secretion from the pancreas in a glucose-dependent manner, meaning they promote insulin release only when blood sugar levels are elevated, which reduces the risk of hypoglycemia

(November 1998)

Pratley [email protected] This article was submitted to Molecular and Structural Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi:10.3390/jcm13133729

May 12, 2026

Determination of trimethylamine-N-oxide in combination with L-carnitine and -butyrobetaine in human plasma by UPLC/MS/MS