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Most people with PWS are mildly mentally retarded (mean IQ: 6070 s), with approximately 40% having borderline mental retardation or low-normal intelligence and approximately 20% having moderate retardation

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Semaglutide is a GLP-1 receptor agonist that regulates appetite and increases satiety by acting on central appetite pathways and slowing gastric emptying

Dahl K, Brooks A, Almazedi F (2021) Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes

The difference between losing 30-38% of your weight from muscle versus 20-23% becomes increasingly significant as total weight loss increases